Health

Self-cleaning medical surfaces
for ventilators

Pneumonia following intubation for mechanical ventilation is among the most frequent nosocomial infections. It is caused by bacterial proliferation on the intubation tubes and subsequent contamination of the patient.

Health
Type of client

Medical devices and technologies, scientific equipment & laboratory furniture manufacturer

OBJECTIveS

Reduce biofilm formation in tubing systems without chemical contamination.

CONSTRAINTS
  • Lifespan of 3 years
  • High biofilm reduction (~90%)
  • Exposure to fluids at variable flow rates
  • Compatibility with medical material
Let's collaborate
with nature ?
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Problem analysis

Why do ventilators promote biofouling?

Medical ventilators create a warm, humid, nutrient-rich environment ideal for microbial growth. Despite sterilization efforts, several structural and biological factors facilitate microbial fouling:

  • Smooth pipe surfaces enable fast bacterial adhesion when in contact with fluids
  • Surface wear over time reduces anti-adhesion properties
  • Bacteria adapt and produce biofilms that reinforce their attachment
  • Nutrients, heat, and stagnant zones create ideal conditions for colonization

AI-driven analysis helped identify the root causes of these issues.

Biological insights

Nature-inspired mechanisms to tackle biofouling challenges

The biomimetic strategies explored for this project draw on natural adaptations that limit microbial adhesion. Examples include:

  • Topographic structures: lotus leaves, shark denticle, dragonfly wings, crab shell, duck feathers
  • Chemical antifouling coatings: Chlorella, Ircinia oros, mussels proteins
  • Hydrophobic coating: Duck feathers, bark
  • Self-assembly of a protective layer: Biomineralisation

Together, these approaches inspire robust and durable anti-fouling surfaces for industrial and medical use.

Asteria then helps you generate ideas of concrete bioinspired concepts leveraging both the various selected biological mechanisms and the modeling of the project's context.

OUTPUT

Bioinspired concepts
generated by Asteria

Dynamic antimicrobial surface via bacterial biomineralization
description
A dynamic surface leveraging bacterial biomineralization to block biofilm growth. A biocompatible coating attracts beneficial bacteria that mineralize the surface, making it inhospitable to pathogens. Self-renewing and chemical-free.
biological model
Non-pathogenic bacteria inducing mineral precipitation
design principal
Biomineralization, wettability control, surface chemistry
Invente a new tech

Materials

Initial biocompatible coating + mineral deposits (e.g., calcium carbonate)

Manufacturing process

Targeted coating application followed by in situ bacterial mineral induction

Existing technology

Dui in posuere lectus in vitae phasellus purus pus.

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Dui in posuere lectus in vitae phasellus purus pus.

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Hierarchical nano-micro surface for biofouling resistance
description
A surface structured at the nano- and micro-scale, inspired by insect leaves and wings. Micro-ridges reduce initial adhesion, while nano-pillars inhibit biofilm formation, creating a hostile environment for bacteria.
biological model
Leaf and insect wing surfaces structuring inducing anti-adhesive properties
design principal
Hierarchical structuring inducing anti-adhesive properties, bacterial adhesion inhibition
Invente a new tech

Materials

Metal or polymer surfaces with micro-ridges and nano-pillars

Manufacturing process

Laser etching, chemical vapor deposition, or selective electrodeposition

Existing technology

Adaptive technologies

Dui in posuere lectus in vitae phasellus purus pus.

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Fusion bionics

Dui in posuere lectus in vitae phasellus purus pus.

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Superhydrophobic self-cleaning coating inspired by lotus
description
A superhydrophobic, self-cleaning pipe coating inspired by the lotus leaf. Its micro/nano texture and low surface energy repel water and dirt. Dynamic covalent bonding allows self-healing and long durability.
biological model
Lotus leaf superhydrophobic surface
design principal
Wettability control, low surface energy, dynamic bonding
Invente a new tech

Materials

Micro/nano structure combined with low-energy surface materials

Manufacturing process

Spray, dip-coating, or chemical vapor deposition

Existing technology

StoColor Lotusan

Dui in posuere lectus in vitae phasellus purus pus.

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NASA Lotus Coating

Dui in posuere lectus in vitae phasellus purus pus.

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Biomimetic antibacterial surface inspired by shark skin
description
Shark skin dermal denticle structure
biological model
Shark skin dermal denticle structure
design principal
Microstructured surface to inhibit bacterial adhesion
Invente a new tech

Polymers (PC, PET, PU, PLA) or metals (titanium, stainless steel) depending on application

Nanoimprint lithography or laser etching of diamond-like microstructure

Existing technology

Sharklet technologies

Dui in posuere lectus in vitae phasellus purus pus.

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Dui in posuere lectus in vitae phasellus purus pus.

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Solution

Designed for R&D innovation,
design and durability

Collaborate with nature

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